Allogenic Stem Cell Transplantation and Total Body Irradiation
نویسندگان
چکیده
منابع مشابه
Allogenic Stem Cell Transplantation and Total Body Irradiation
The clinical importance of bone marrow transplantation has increased considerably in recent decades. More than 450 centers for bone marrow transplantation now exist worldwide, performing more than 5000 transplantations per year. The number of transplant centers and patients has increased dramatically in Turkey in the last several years. When transplant donor and recipient are different individu...
متن کاملTotal Body Irradiation (TBI) using Helical Tomotherapy in children and young adults undergoing stem cell transplantation
BACKGROUND Establishing Total Body Irradiation (TBI) using Helical Tomotherapy (HT) to gain better control over dose distribution and homogeneity and to individually spare organs at risk. Because of their limited body length the technique seems especially eligible in juvenile patients. PATIENTS AND METHODS The cohort consisted of 10 patients, 6 female and 4 male, aged 4 - 22 y with acute lymp...
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Background: Bone marrow transplantation (BMT) is considered as a curative therapy for a broad range of diseases. However, complications such as relapse and graft versus host disease (GVHD) may be observed following BMT. Chimerism analysis serves as a reliable indicator of transplant outcome. Complete chimerism refers to the complete replacement of hematopoietic system by donor cells, while mixe...
متن کاملTotal-body irradiation in the conditioning regimens for autologous stem cell transplantation in lymphoproliferative diseases.
We review the rationale for, and the results of, clinical trials on chemoradiotherapy-based pretransplant regimens for non-Hodgkin's lymphomas, Hodgkin's disease and multiple myeloma. What clearly emerges from this review is the lack of any conclusive evidence that total-body irradiation (TBI)-containing regimens are better than chemotherapy alone in diseases which are considered to be radiosen...
متن کاملTotal-body irradiation for bone marrow transplantation.
Total-body irradiation (TBI), when given as part of bone marrow transplantation (BMT), works by enhancing immune suppression and by exerting a tumoricidal effect. The modality has been made less toxic because of new approaches to delivering TBI, such as fractionation, and partial organ shielding, Colleen Lawton, MD, professor at the Medical College of Wisconsin, Milwaukee, said at the 1998 Amer...
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ژورنال
عنوان ژورنال: Turkish Journal of Oncology
سال: 2016
ISSN: 1300-7467
DOI: 10.5505/tjo.2016.1499